On Dec 31, 2019, the Wuhan Municipal Health Commission (Wuhan, China), reported a cluster of cases of pneumonia to WHO. A novel coronavirus was identified—severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)—and the outbreak was declared as a Public Health Emergency of International Concern in January, 2020. The virus subsequently spread rapidly throughout China and other countries worldwide, and on March 11, 2020, the outbreak was declared a pandemic. Since March 11, 2020, the virus has continued to spread, causing substantial morbidity and mortality in many countries.
In previous outbreaks of other coronavirus infections, such as severe acute respiratory syndrome and Middle East respiratory syndrome, serious complications were reported in pregnant women.
During the 2009 influenza A H1N1 pandemic, pregnant women accounted for 5% of US deaths, while representing only 1% of the US population.
However, despite more than 18 million reported cases of COVID-19 worldwide,
understanding of the effect of SARS-CoV-2 on pregnant women, fetuses, and infants is incomplete.
A systematic review and meta-analysis of mainly small case series reported that a high proportion of women with confirmed COVID-19 infection had preterm birth (